منابع مشابه
The isolation of mutagen-sensitive nuv mutants of Aspergillus nidulans and their effects on mitotic recombination.
More than 200 mutants of Aspergillus nidulans were isolated as hypersensitive to the monofunctional alkylating agent MNNG and/or UV-irradiation (designated nuv mutants). Of these, 23 were selected for further characterization. All were markedly hypersensitive to both MNNG and the quasi-UV-mimetic mutagen 4-NQO. The hypersensitive phenotype of each mutant was shown to result from mutation of a s...
متن کاملAnalysis of mitotic nondisjunction with Aspergillus nidulans.
Two methods to detect the induction of nondisjunction with a diploid stable strain of A. nidulans are described. The first method gives only qualitative results, while the second method is quantitative and dose-effect curves can be done. Some physiological parameters affecting the induction of nondisjunction can also be studied, because either quiescent or germinating conidia can be treated wit...
متن کاملEnhancers of conidiation mutants in Aspergillus nidulans.
Mutants at a number of loci, designated sthenyo, have been isolated as enhancers of the oligoconidial mutations at the medA locus. Two loci have been mapped: sthA on linkage group I, and sthB on linkage group V. Two probable alleles have been identified at each locus but two further mutants were unlinked to either sthA or sthB. Neither sthA nor sthB mutants have conspicuous effects on morpholog...
متن کاملIsolating Auxotrophic Mutants in Aspergillus nidulans
A method for the selection of auxotrophic mutants in Aspergillus nidulans using N-glycosyl-polifungin has been developed. The method results in about 9000fold enrichment. All types of auxotrophs were obtained. Under certain conditions preferential selection of nucleic acid hydrolysate-requiring auxotrophs was observed. The frequency of occurrence of these mutants was about 50 % of all colonies ...
متن کاملRadiation effects and mitotic recombination in diploids of Aspergillus nidulans.
NTENSE gamma-radiation of conidia has been found to produce a very high I frequenc y of abnormal, sectoring colonies in heterozygous diploids of Aspergillus nidulans (=FER 1960). To obtain information about the nature of the radiation effects which cause the formation of colonies with many large segregant sectors, a detailed analysis of a relatively small number of such sectoring colonies has b...
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ژورنال
عنوان ژورنال: Genetical Research
سال: 1975
ISSN: 0016-6723,1469-5073
DOI: 10.1017/s0016672300016049